When a medication is administered by a different route than the one for which it has been approved, it is called a ”non official”, ”non approved”, ”Off Label” or alternative route of administration. Many examples come to mind, such as an oral tablet given rectally, ophtalmic drops given orally or a parenteral solution given orally.
Comments from Dr Peter Dvorak, Pharm.D.,DESS.,CTH. The following documents (links) will help the health professional to determine which transdermal patches can be cut or modified. However, the context in which the patches will be used, should always be evaluated first. In a hospital setting, the handling is carried out by qualified personnel according to an
Tablet Crushing Considerations in Geriatrics M. Fodil a,∗ , A. Fillette b, C. Trivalle c a Pharmacist practitioner attached. Pharmacy Department, Paul-Brousse University Hospital, AP—HP, 14, avenue P.V.-Couturier, 94804 Villejuif cedex, France b Pharmacy intern. Pharmacy Department, Paul-Brousse University Hospital, 14, avenue P.V.-Couturier, AP—HP, 94804 Villejuif cedex, France c Geriatrician, hospital practitioner. Department of Geriatrics,
What to do with oral formulations that cannot be cut or crushed? Authorr: Dr Peter Dvorak. Pharm.D.,DESS.,CTH. There are several situations where changing an oral formulation may be useful or even necessary. However, these manipulations can sometimes have disastrous effects on the health of patients. Currently, to our knowledge, there is no guide in Canada